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K52.8 – Non-infective Gastroenteritis & Colitis
K52.8 is an ICD-10 diagnosis code for other specified non-infective gastroenteritis and colitis. It describes inflammation of the gastrointestinal tract without an infectious cause.
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K52.8 is an ICD-10 diagnosis code for other specified non-infective gastroenteritis and colitis. It describes inflammation of the gastrointestinal tract without an infectious cause.
What does the diagnosis code K52.8 mean?
The ICD-10 code K52.8 stands for other specified non-infective gastroenteritis and colitis. It belongs to the group of non-infective inflammations of the gastrointestinal tract and is used when inflammation of the stomach, small intestine, or colon is present that is not caused by bacteria, viruses, or other pathogens, and that can be assigned to a more specific sub-diagnosis.
Causes
The conditions classified under K52.8 can have various non-infective causes:
- Food intolerances (e.g., lactose intolerance, gluten intolerance)
- Allergic reactions to certain foods or substances
- Drug-induced colitis, triggered by antibiotics, NSAIDs, or other medications
- Radiation colitis following radiotherapy in the abdominal area
- Microscopic colitis (collagenous or lymphocytic colitis)
- Eosinophilic gastroenteritis, a rare condition with excessive infiltration of eosinophilic granulocytes into the intestinal wall
- Chemical or toxic influences
Symptoms
The symptoms of non-infective gastroenteritis or colitis can vary depending on the cause and the affected section of the intestine. Common complaints include:
- Diarrhea, sometimes chronic or recurring
- Abdominal pain and cramps
- Blood or mucus in the stool (depending on the cause)
- Nausea and vomiting
- Bloating and flatulence
- General malaise and fatigue
Diagnosis
Diagnosis is made through a combination of:
- Medical history: dietary habits, medication use, pre-existing conditions
- Laboratory tests: blood count, inflammatory markers (CRP, ESR), stool analysis
- Colonoscopy with biopsy for histological examination
- Imaging procedures such as ultrasound or MRI if needed
- Exclusion of infectious causes through pathogen detection in stool
Treatment
Treatment is tailored to the underlying cause:
- Dietary adjustments: avoidance of triggers such as lactose, gluten, or specific foods
- Discontinuation or change of medications that triggered the colitis
- Drug therapy: corticosteroids, mesalazine, or budesonide for inflammatory forms
- Probiotics to support intestinal flora
- Symptomatic treatment: antispasmodics for cramping, electrolyte replacement for diarrhea
Clinical Relevance
The ICD-10 code K52.8 is clinically significant as it covers a broad group of intestinal diseases not caused by infections. Accurate diagnosis is essential to initiate the correct therapy and to prevent chronic progression. Persistent or severe symptoms should always be assessed by a specialist.
References
- World Health Organization (WHO): International Classification of Diseases, 10th Revision (ICD-10). Chapter XI: Diseases of the Digestive System (K00–K93). Geneva: WHO.
- Fernández-Bañares F. et al.: Microscopic Colitis: A Review. Digestive Diseases and Sciences, 2022.
- Lacy B.E. et al.: ACG Clinical Guideline: Management of Irritable Bowel Syndrome. American Journal of Gastroenterology, 2021.
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