-
DE
Calciferols (vitamin D) - forms, functions and importance for health and immune defence
Calciferols, known as vitamin D, are essential for bones, the immune system and cell health. Find out more about forms, functions, deficiency symptoms and optimal intake.
Add as Preferred SourceThings worth knowing about "Calciferols"
Calciferols, known as vitamin D, are essential for bones, the immune system and cell health. Find out more about forms, functions, deficiency symptoms and optimal intake.
Calciferols are a group of fat-soluble compounds that are summarised under the generic term vitamin D. They play a central role in calcium and phosphate metabolism and are essential for bone stability, cell function and immune defence. The two most important biologically active forms are:
-
Vitamin Dâ‚‚ (ergocalciferol): Of plant origin
-
Vitamin D₃ (cholecalciferol): Of animal origin or produced by the body itself through UVB radiation from the sun
Both forms are converted in the liver to 25-hydroxyvitamin D (calcidiol) and then converted in the kidneys to the active hormone form 1,25-dihydroxy-vitamin D (calcitriol).
Functions of calciferols (vitamin D)
Calciferols have far-reaching physiological effects, including:
-
Regulation of the calcium and phosphate balance for stable bones and teeth
-
Strengthening the immune system, in particular by modulating T cells and anti-inflammatory cytokines
-
Influencing gene expression in over 200 genes
-
Support of muscle function and the nervous system
-
Involvement in the prevention of chronic diseases such as osteoporosis, autoimmune diseases, type 1 diabetes and cardiovascular diseases
Vitamin D deficiency - A widespread problem
Despite its importance, vitamin D deficiency is widespread worldwide, especially in regions with low sun exposure or in people with dark skin colour, obesity, chronic diseases or impaired kidney function.
Possible consequences of a deficiency:
-
Bone softening (osteomalacia) or rickets in children
-
Muscle weakness, fatigue and immunodeficiency
-
Increased risk of infections, depression, autoimmune diseases and high blood pressure
Intake and supplementation
The body can synthesise vitamin D₃ itself, but requires sufficient sunlight (UVB radiation) on the skin. In the winter months or with limited sun exposure, supplementation is often necessary.
Recommended intake:
-
800-2,000 I.U. (International Units) daily, depending on age, lifestyle and blood values
-
Optimal blood value: 25(OH)D level of 30-50 ng/ml (75-125 nmol/l)
Vitamin D is often taken in combination with vitamin K2 to support targeted calcium utilisation in the bones and prevent calcification of the blood vessels.
Literature references:
-
Holick, M. F. (2007). ""Vitamin D Deficiency."" New England Journal of Medicine.
-
RKI (2023). ""Vitamin D supply in Germany."" Robert Koch Institute.
-
Pludowski, P. et al. (2018). ""Vitamin D supplementation guidelines."" Nutrients.
Building Blocks for a Healthy Life
As an integrated manufacturer, we develop & produce evidence-based, patented, and non-patented formulations. We work exclusively with plant and natural extracts according to the strictest purity & quality standards.
The combination of science & modern technology with the laws of nature creates solutions consistently tailored to humans – for the highest good: health.
Skip product gallery
Subscription available
Floral
For Healthy Oral Flora & Dental Care
Formulated lozenges with Dentalac®, lactic acid bacteria, and Lactoferrin CLN®30 lozenges
Regular price:
22,90 €
Discount
Subscription available
Lactoferrin 60 Capsules
For your universal protection
As one of the most valuable proteins in the body, lactoferrin is a natural component of the immune system.
60 Capsules
Sale price:
50,00 €
Regular price:
59,90 €
Discount
Subscription available
Multivitamin Mineral Complex
Daily basic supply: the complete spectrum of micronutrients
Natural multivitamin complex for the immune system, energy, and central body functions
30 Capsules
Sale price:
27,90 €
Regular price:
29,90 €
Subscription available
Natural Iron
For your iron balance
Specially formulated for your iron balance with plant-based curry leaf iron, Lactoferrin CLN®, and natural Vitamin C from rose hips.
30 Capsules
Regular price:
35,90 €
Most read entries
3 Posts in this encyclopedia categoryMagnesiumcarbonat
Magnesiumcarbonat ist eine anorganische Magnesiumverbindung mit säure-neutralisierender (antazidischer) Wirkung. Erfahre mehr über Vorteile, Einsatzgebiete und Unterschiede zu besser resorbierbaren Magnesiumformen.
Calorie content
The choice of food influences our energy intake. The calorie content varies greatly - some provide little energy, others a lot.
Cologne list
The Cologne List ® is an important initiative in competitive sports that offers athletes guidance in the selection of nutritional supplements.