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Androgens are male sex hormones produced in the testes, ovaries, and adrenal cortex that regulate numerous vital body functions in both sexes.
Androgens are male sex hormones produced in the testes, ovaries, and adrenal cortex that regulate numerous vital body functions in both sexes.
Androgens are a group of steroid hormones best known as male sex hormones. The most potent and well-known androgen is testosterone. However, androgens are not exclusive to males – the female body also produces them in smaller amounts. They are primarily synthesized in the testes (in men), the ovaries (in women), and the adrenal cortex in both sexes.
The most important androgens include testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone (DHEA), and androstenedione.
Androgens fulfill a wide range of functions in the body:
Androgens also play an important role in the female body. They serve as precursor molecules for the synthesis of estrogens and influence libido, bone strength, and general well-being. An excess of androgens in women, however, can lead to health problems, as seen in polycystic ovary syndrome (PCOS).
Elevated androgen levels can cause the following symptoms in women:
Common causes include PCOS, adrenal gland disorders, or androgen-producing tumors.
A deficiency of androgens, particularly testosterone, can lead to a condition known as hypogonadism in men. Typical symptoms include:
Androgen levels are determined through a blood test. Measurements typically include total testosterone, free testosterone, DHEA-S, and other hormone levels. Results are always interpreted in clinical context and with consideration of the patient's age and sex.
Synthetic androgens and testosterone preparations are used medically for:
The misuse of androgens – for example, anabolic steroids in sports – carries significant health risks, including liver damage, cardiovascular disease, and hormonal imbalances.
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