Premium Nahrungsergänzungsmittel | artgerecht

Desensitisation Injection – Allergy Immunotherapy

A desensitisation injection is a specific immunotherapy used to treat allergies. It gradually reduces the immune system´s overreaction to allergens for long-term relief.

Regular tips about health Regular tips about health

Things worth knowing about "Desensitisation Injection"

A desensitisation injection is a specific immunotherapy used to treat allergies. It gradually reduces the immune system´s overreaction to allergens for long-term relief.

What is a Desensitisation Injection?

A desensitisation injection – also known as allergen immunotherapy (AIT) or specific immunotherapy (SIT) – is a medical treatment in which patients with allergies are gradually exposed to increasing amounts of the allergen that triggers their symptoms. The goal is to reduce or eliminate the immune system´s overreaction over the long term. It is considered the only causal treatment available for allergies, addressing the underlying mechanism rather than just managing symptoms.

How Does Desensitisation Work?

During desensitisation treatment, the patient is given gradually increasing doses of the relevant allergen at regular intervals. Over time, the immune system learns to tolerate the allergen without mounting an allergic response. This process is known as immune tolerance.

There are two main methods of administration:

Subcutaneous Immunotherapy (SCIT): The allergen extract is injected under the skin, typically at a doctor´s office or allergy clinic.
Sublingual Immunotherapy (SLIT): The allergen is administered as drops or dissolving tablets placed under the tongue, often allowing home administration after initial supervision.

Indications

Desensitisation injections are used to treat a range of allergic conditions, including:

Pollen allergy (e.g., birch or grass pollen)
House dust mite allergy
Pet dander allergy
Insect venom allergy (e.g., bee or wasp stings)
Mould allergy

Treatment Duration and Process

Treatment typically consists of two phases:

Build-up phase: The allergen dose is gradually increased over several weeks to months, depending on the protocol used.
Maintenance phase: The maximum tolerated dose is administered at regular intervals, usually over a total period of 3 years.

Noticeable symptom relief may occur as early as the first treatment season, but the full benefit of the therapy is usually achieved after completing the entire 3-year course.

Effectiveness and Benefits

Numerous clinical studies have demonstrated the effectiveness of allergen immunotherapy. Key benefits include:

Long-lasting reduction in allergy symptoms
Decreased need for allergy medications such as antihistamines
Prevention of asthma development in children with hay fever
Prevention of sensitisation to new allergens

Side Effects and Risks

Desensitisation treatment is generally well tolerated. Possible side effects include:

Local reactions at the injection site (redness, swelling, itching)
Mild systemic reactions such as sneezing or itchy eyes
In rare cases: severe allergic reactions (anaphylaxis) – which is why injections are always administered under medical supervision

Who is Suitable for Treatment?

Desensitisation injections are suitable for children aged approximately 5 years and older, as well as adults. The treatment is generally not recommended for patients with:

Severe uncontrolled asthma
Serious cardiovascular conditions
Certain medications (e.g., beta-blockers)
New initiation during pregnancy

References

Pfaar O. et al. – Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases. Allergo Journal International, 2014.
World Allergy Organization (WAO) – White Book on Allergy, 2013.
Jutel M. et al. – International consensus on allergy immunotherapy. Journal of Allergy and Clinical Immunology, 2015.

Building Blocks for a Healthy Life

As an integrated manufacturer, we develop & produce evidence-based, patented, and non-patented formulations. We work exclusively with plant and natural extracts according to the strictest purity & quality standards.
The combination of science & modern technology with the laws of nature creates solutions consistently tailored to humans – for the highest good: health.