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E122 Carmoisine: Food Dye, Effects & Safety

E122 (Carmoisine) is a synthetic red azo dye used as a food additive to colour foods and beverages. It has been linked to increased hyperactivity in children.

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Things worth knowing about "E122"

E122 (Carmoisine) is a synthetic red azo dye used as a food additive to colour foods and beverages. It has been linked to increased hyperactivity in children.

What is E122 (Carmoisine)?

E122, commonly known as Carmoisine or Azorubine, is a synthetic red azo dye used in the food industry as a colouring agent. It gives foods and beverages a vibrant red to dark-red hue. In the European Union, E122 is an approved food additive regulated by the European Food Safety Authority (EFSA).

Occurrence and Uses

E122 is used in a wide range of processed food products, including:

Sweets and confectionery
Fruit yoghurts and desserts
Soft drinks and flavoured beverages
Jams and jellies
Pastries and baked goods
Marinades and sauces

The dye is water-soluble and heat-stable, making it well suited for industrial food processing.

Chemical Properties

Carmoisine belongs to the class of azo dyes, characterised by a distinctive azo group (-N=N-). Its chemical name is disodium 4-hydroxy-3-(4-sulfonato-1-naphthylazo)naphthalene-1-sulfonate. It is a fully synthetic dye with no connection to natural food colours.

Health Aspects and Safety

Hyperactivity in Children

EFSA and the UK Food Standards Agency (FSA) have reviewed studies suggesting a possible link between the consumption of certain azo dyes -- including E122 -- and increased hyperactivity in children. As a result, since 2010 the EU has required a warning label on products containing specific azo dyes: May have an adverse effect on activity and attention in children.

Pseudo-Allergic Reactions

In sensitive individuals, particularly those with an aspirin intolerance or existing allergies, E122 may trigger pseudo-allergic reactions. These can include skin rashes (urticaria), itching, or in rare cases difficulty breathing.

Permitted Maximum Levels

EFSA has established an Acceptable Daily Intake (ADI) of 4 mg per kg of body weight per day for E122. The maximum permitted levels in various food categories within the EU are governed by Regulation (EC) No 1333/2008.

Labelling Requirements

Foods containing E122 must declare this additive in the ingredients list, either under the name Carmoisine or the code E122. Products aimed at children must additionally carry the above-mentioned warning statement.

Alternatives

Natural alternatives to E122 include colourants such as beetroot red (E162), carmine (E120), or other plant-based extracts, which are preferred by some consumers and manufacturers seeking cleaner labels.

References

European Food Safety Authority (EFSA) - Scientific Opinion on the re-evaluation of Azorubine/Carmoisine (E 122) as a food additive (2009). Available at: https://www.efsa.europa.eu
European Parliament and Council of the EU - Regulation (EC) No 1333/2008 on food additives.
McCann, D. et al. - Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial. The Lancet, 370(9598), 1560-1567 (2007).

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