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Embryotox – Medications in Pregnancy and Breastfeeding

Embryotox is a scientific database on medication safety during pregnancy and breastfeeding. It provides evidence-based information for healthcare professionals and patients.

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Things worth knowing about "embryotox"

Embryotox is a scientific database on medication safety during pregnancy and breastfeeding. It provides evidence-based information for healthcare professionals and patients.

What is Embryotox?

Embryotox is an independent, scientific information platform and database operated by the Charite – Universitaetsmedizin Berlin. It provides comprehensive, evidence-based information on the compatibility and safety of medications, vaccines, and other substances during pregnancy and breastfeeding. The platform is designed for both healthcare professionals and affected patients.

Background and Purpose

Many pregnant and breastfeeding women need to take medications, whether to treat chronic conditions or acute health issues. Knowing which medicines are safe during these sensitive phases is of the utmost importance – for the health of the mother as well as for the development of the unborn child or infant.

Embryotox was established to close this information gap. The database collects and evaluates scientific studies, case reports, and international specialist literature in order to provide well-founded recommendations on medication safety.

Content and Features

Drug evaluations: Detailed monographs on a wide range of active substances, including risk assessments for pregnancy and breastfeeding.
Search function: Targeted search by medication, active ingredient, or indication.
Regular updates: Entries are continuously revised based on the latest scientific findings.
Advisory service: Telephone and written consultations by the Pharmacovigilance and Counselling Centre for Embryonal Toxicology for complex clinical questions.

Importance for Pregnant and Breastfeeding Women

During pregnancy, special caution is required when taking medications, as many active substances can cross the placental barrier and affect the developing child. During breastfeeding, substances may pass into breast milk and reach the infant. Embryotox helps to assess these risks and supports informed decision-making.

Typical topics covered in the database include:

Pain relievers (e.g. paracetamol, ibuprofen)
Antibiotics and antiviral agents
Antidepressants and psychotropic drugs
Thyroid medications
Blood pressure medications
Vaccines and their compatibility

Scientific Basis

All evaluations within Embryotox are based on a systematic review of the available scientific literature. The entries are created and reviewed by specialists in pharmacology, gynecology, pediatrics, and other medical disciplines. The platform is independent from the pharmaceutical industry, ensuring neutral and patient-focused information.

Access and Usage

The Embryotox database is freely accessible to the public at www.embryotox.de. It can be used by physicians, midwives, pharmacists, and affected women. For particularly complex cases, the advisory center at the Charite is available for direct consultation.

References

Charite – Universitaetsmedizin Berlin: Embryotox – Pharmacovigilance and Counselling Centre for Embryonal Toxicology. Available at: www.embryotox.de
Schaefer C, Peters P, Miller RK (eds.): Drugs During Pregnancy and Lactation. 3rd edition. Academic Press, 2015.
World Health Organization (WHO): Guidelines for the treatment of common illnesses in pregnancy. WHO Press, Geneva.

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