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Grape seed extract - effect, application and study situation
Grape seed extract is rich in OPC and is known for its antioxidant properties. Find out more about its effects, use and scientific background.
Add as Preferred SourceThings worth knowing about "Grape seed extract"
Grape seed extract is a concentrated plant substance obtained from the seeds of red grapes.
Grape seed extract is particularly rich in oligomeric proanthocyanidins (OPCs), a group of secondary plant substances with a strong antioxidant effect. This substance has attracted a great deal of attention in naturopathy and functional medicine in recent years, as it is said to have numerous health-promoting properties - particularly with regard to cell protection, skin health and vascular function.
The antioxidant capacity of OPC is said to help neutralise free radicals that can be caused by environmental factors such as UV radiation, stress or pollutants. There is also evidence that grape seed extract has an anti-inflammatory effect and improves microcirculation in the capillaries - which can be particularly relevant in cases of venous insufficiency or tired legs. The extract is also frequently used as a natural cell protector in the field of anti-ageing.Grape seed extract is usually taken orally in the form of capsules or powders. The dosage varies depending on the product and the intended benefit; typical daily doses are between 100 and 300 mg of OPC. As this is a highly concentrated natural product, it is important to ensure high-quality raw materials and a standardised OPC specification. Clinical studies on the exact effectiveness and bioavailability are still underway, but initial results support the observed effects.Effects of grape seed extract:- Antioxidant cell protection (neutralisation of free radicals)
- Support for vascular health and circulation
- Contributes to skin protection and anti-ageing
- Possible positive influence on the immune system
Application and dosage:
- Typically as a dietary supplement in capsule or powder form
- Dosage usually between 100-300 mg OPC daily
- Ideally taken with a fatty meal for better absorption
Notes:
- High-quality extracts contain ≥ 95 % polyphenols
- OPC is sensitive to light and oxygen - ensure lightproof packaging
- consult your doctor if you are taking blood thinners
Literature references:
- Bagchi, D. et al. (2000): Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation. Free Radical Biology and Medicine.
- Terra, X. et al. (2007): Grape-seeded procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet. The Journal of Nutritional Biochemistry.
- Nassiri-Asl, M., & Hosseinzadeh, H. (2009): Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds. Phytotherapy Research.
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