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Hand, foot and mouth disease is a contagious viral illness that mainly affects young children, causing blisters on the hands, feet, and sores inside the mouth.
Hand, foot and mouth disease is a contagious viral illness that mainly affects young children, causing blisters on the hands, feet, and sores inside the mouth.
Hand, foot and mouth disease (HFMD) is a common, contagious viral infection that primarily affects infants and children under the age of five. It is characterized by a distinctive rash or blisters on the hands and feet, as well as painful sores in the mouth. In most cases, the illness is mild and resolves on its own within one to two weeks.
HFMD is caused by enteroviruses, most commonly Coxsackievirus A16 and Enterovirus 71 (EV-A71). The viruses spread easily through:
Outbreaks occur worldwide but are most common in summer and autumn. Children in nurseries, daycare centres, and schools are at particularly high risk due to close contact with others.
After an incubation period of three to seven days, the following symptoms typically appear:
Mouth sores can make swallowing painful, causing children to refuse food and drink. In rare cases, particularly with Enterovirus 71 infections, serious complications such as viral meningitis (inflammation of the membranes surrounding the brain) or encephalitis (brain inflammation) may develop.
Diagnosis is usually made clinically, based on the characteristic appearance of the blisters and rash, together with the patient's age and medical history. Laboratory tests are generally not needed. In severe or atypical cases, a throat swab or stool sample may be tested to identify the specific virus responsible.
There is no specific antiviral treatment for HFMD. Management is therefore supportive and symptomatic:
Infected children should stay home from school or daycare until they are fever-free and no new blisters are appearing, in order to prevent further spread. A vaccine against Enterovirus 71 is approved in some Asian countries but is not yet available in Europe or North America as of 2024.
Since no vaccine is widely available outside of Asia, good hygiene practices are the most effective preventive measures:
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