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Inflammation markers - What blood values reveal about silent inflammation

Inflammation markers such as CRP, IL-6 or TNF-α show silent inflammation in the body. Find out which markers are important and how you can influence them.

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Things worth knowing about "Inflammation markers"

Inflammation markers are measurable substances in the blood that indicate inflammatory processes in the body - both in acute infections and in chronic silent inflammation (silent inflammation).

In modern preventive and micronutrient medicine, inflammatory markers are becoming increasingly important, as they help to to recognise subclinical inflammatory conditions at an early stage, which are associated with cardiovascular diseases, diabetes, autoimmune processes or neurodegenerative diseases are associated.

The most important laboratory values include the C-reactive protein (CRP) - especially in the highly sensitive variant (hs-CRP) -, Interleukin-6 (IL-6), tumour necrosis factor alpha (TNF-α), and fibrinogen, Ferritin and Zonulin. While acute inflammation leads to highly elevated values, a slight but persistent elevation (e.g. hs-CRP between 1 and 3 mg/l) often indicates systemic low-grade inflammation - a silent risk factor.

In order to regulate inflammatory markers, targeted measures such as an anti-inflammatory diet, sufficient omega-3 fatty acids, curcumin, magnesium, stress reduction and the strengthening of the intestinal barrier. Laboratory diagnosis of these markers provides valuable information for preventive or therapeutic approaches - especially in cases of unexplained fatigue, joint complaints, skin problems or suspected autoimmune disorders.

Important inflammation markers at a glance:

  • hs-CRP (high-sensitivity C-reactive protein): Marker for chronic silent inflammation
  • IL-6 (interleukin-6): Cytokine with proinflammatory effect
  • TNF-α (tumour necrosis factor alpha): Key messenger in systemic inflammation
  • Zonulin: Marker for intestinal permeability ("Leaky Gut")
  • Other markers: Ferritin, Fibrinogen, Lipopolysaccharides (LPS)

Influence of diet & lifestyle:

  • Omega-3 fatty acids (EPA/DHA) lower IL-6 and TNF-α
  • Curcumin, OPC, Spermidine with regulatory influence
  • Fasting, Exercise, Sleep and Build up your gut promote balance
  • Sugar avoidance and reduction of trans fats have an anti-inflammatory effect
  • Lab tests recommended over several months to monitor progress

Literature references

  • Pearson, T.A. et al. (2003): Markers of inflammation and cardiovascular disease. Circulation.
  • Calder, P.C. (2013): Omega-3 fatty acids and inflammatory processes. Nutrients.
  • Hotamisligil, G.S. (2006): Inflammation and metabolic disease. Nature.
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