Cholesterol - a fatty substance important for cells, hormones & heart health

Cholesterol is a vital substance for cell structure and hormone production. Too much LDL cholesterol increases the risk of a heart attack - diet and exercise help to regulate this.

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Wissenswertes über "Cholesterol"

Cholesterol is a fat-like substance (lipid molecule) that is vital for cell membranes and is both produced in the liver and absorbed through food.

In addition to its function as a building block for the body's cell membranes, cholesterol serves as a starting material for the production of hormones such as oestrogen, testosterone and cortisol and plays a central role in the formation of bile acids, which are required for the digestion of fat.Cholesterol is transported in the blood in the form of lipoproteins, which consist of fats and proteins.

Cholesterol is often associated with health risks such as heart attacks, especially if the ratio of LDL cholesterol (the "bad" cholesterol) to HDL cholesterol (the "good" cholesterol) is too high.

LDL cholesterol (low density lipoprotein) is colloquially referred to as "bad cholesterol", as it can be deposited in the vessel walls in excess and form plaques or calcifications there, which increase the risk of arteriosclerosis (vascular calcification). This can lead to circulatory disorders, heart attacks or strokes.
HDL cholesterol (high density lipoprotein) is considered "good cholesterol" as it transports excess cholesterol from the tissues back to the liver and thus has a vasoprotective effect.

The most common causes of high cholesterol levels include an unhealthy diet, lack of exercise, smoking, genetic predisposition and chronic diseases such as diabetes. Stress and obesity can also have a negative effect on cholesterol levels. Foods rich in fibre such as oatmeal, fruit, vegetables and pulses can help with high cholesterol levels. They bind cholesterol in the intestine and promote its excretion. Saturated fatty acids, which are found in avocados, nuts, olive oil and fish, help to lower LDL. Omega-3 fatty acids from fish or algae oil are known to lower triglyceride levels (subgroup of fats) and promote heart health.

Important features of cholesterol:

Issential for cell membranes, hormones, vitamin D, bile acids
Differentiated into LDL (bad) and HDL (good)
Elevated levels increase the risk of arteriosclerosis and heart attack
Regulation via lifestyle, diet and, if necessary, medication
. Medication
Part of every routine blood test for cardiovascular prophylaxis

Literature references

Grundy, S. M. (2003). "Cholesterol and coronary heart disease: a new era." JAMA.
Gotto, A. M. (1997). "Therapeutic approaches to the management of hypercholesterolemia." Circulation.
German Society of Cardiology (2021). "Guideline on lipid therapy and prevention of cardiovascular disease."