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Supportive Therapy – Definition & Measures

Supportive therapy encompasses all measures that accompany primary treatment to relieve side effects and maintain quality of life. It is an essential part of modern patient care.

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Things worth knowing about "Supportive therapy"

Supportive therapy encompasses all measures that accompany primary treatment to relieve side effects and maintain quality of life. It is an essential part of modern patient care.

What is Supportive Therapy?

Supportive therapy (also called supportive care) refers to all medical, nursing, and psychosocial measures used alongside a primary treatment. Its purpose is to manage side effects, preserve the quality of life of patients, and ensure that the main treatment can be carried out as planned. Supportive therapy does not target the underlying disease itself, but rather supports the body and overall well-being of the patient throughout the entire treatment process.

Areas of Application

Supportive therapy is applied across many medical disciplines, but is especially prominent in oncology (cancer medicine), where it accompanies chemotherapy, radiation therapy, and other intensive treatment modalities. It also plays a vital role in the management of chronic diseases, post-operative recovery, and intensive care medicine.

  • Oncology: Managing nausea, vomiting, fatigue, and infections during chemotherapy
  • Haematology: Blood transfusions and growth factors to support blood cell production
  • Chronic diseases: Pain management, nutritional support, and psychological counselling
  • Intensive care: Respiratory support, circulatory stabilisation, and nutritional therapy
  • Palliative care: Symptom control and maintenance of quality of life in advanced disease stages

Goals of Supportive Therapy

The core objectives of supportive therapy include:

  • Relief from treatment-related symptoms and side effects
  • Maintenance or improvement of quality of life
  • Ensuring the primary therapy can be administered at the planned dose and frequency
  • Prevention and management of complications
  • Psychosocial support for patients and their families
  • Promotion of treatment adherence

Typical Measures and Methods

Pharmacological Support

Pharmacological supportive care measures include a wide range of agents:

  • Antiemetics to prevent or treat nausea and vomiting (e.g. ondansetron, metoclopramide)
  • G-CSF (granulocyte colony-stimulating factors) to support white blood cell production
  • Analgesics (pain medications) following the WHO analgesic ladder
  • Antibiotics, antifungals, and antivirals for infection prevention and treatment
  • Corticosteroids for anti-inflammatory effects and symptom control
  • Bisphosphonates to protect bone health in patients with bone metastases

Nutritional Therapy

Adequate nutrition is particularly important during serious illness. Clinical nutritional therapy includes oral nutritional supplements, enteral feeding via tube, and parenteral (intravenous) nutrition when normal food intake is not possible.

Psycho-oncological and Psychosocial Support

Psychological burdens such as anxiety, depression, or social isolation are common in seriously ill patients. Psycho-oncological counselling, social services, and self-help groups are integral components of a comprehensive supportive care concept.

Physiotherapy and Exercise Therapy

Targeted physical exercises and physiotherapeutic measures help counteract therapy-related muscle loss, maintain physical function, and reduce cancer-related fatigue.

Complementary Medicine

Complementary approaches such as acupuncture, relaxation techniques, or selected herbal preparations can enrich supportive care when carefully chosen and discussed with a physician. Potential interactions with primary therapies must always be considered.

Distinction from Palliative Care

Although supportive therapy and palliative care share similar principles, there is an important distinction: supportive therapy accompanies an ongoing curative or life-prolonging treatment, while palliative care focuses primarily on symptom control and quality of life in advanced, incurable stages of disease. In clinical practice, the two approaches frequently overlap.

Importance for Treatment Outcomes

Consistently applied supportive therapy makes a significant contribution to the overall success of treatment. It enables patients to better tolerate intensive therapies and can help prevent treatment discontinuation. Numerous studies demonstrate that high-quality supportive care not only improves quality of life but may also have a positive impact on overall survival.

References

  1. Leitlinienprogramm Onkologie (AWMF, German Cancer Society, German Cancer Aid): S3 Guideline on Supportive Therapy in Oncological Patients (2020). Available at: https://www.leitlinienprogramm-onkologie.de
  2. Berger AM et al.: NCCN Clinical Practice Guidelines in Oncology: Supportive Care (2023). National Comprehensive Cancer Network.
  3. Schrijvers D, Prommer EE (eds.): The ESMO Handbook of Oncological Emergencies. European Society for Medical Oncology (ESMO), 2016.

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