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Insomnia – Causes, Symptoms and Treatment

Insomnia is a sleep disorder characterized by difficulty falling or staying asleep, significantly affecting quality of life and daily functioning.

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Things worth knowing about "Insomnia"

Insomnia is a sleep disorder characterized by difficulty falling or staying asleep, significantly affecting quality of life and daily functioning.

What is Insomnia?

Insomnia is one of the most common sleep disorders worldwide. It is defined by persistent difficulties in falling asleep, staying asleep, or waking up too early, even when adequate time and opportunity for sleep are available. The daytime consequences include fatigue, difficulty concentrating, irritability, and reduced performance at work or in daily activities.

Insomnia is classified as acute when it lasts less than three months, and as chronic when it occurs at least three nights per week for three months or longer.

Causes

The causes of insomnia are diverse and can be psychological, physical, or lifestyle-related:

Psychological factors: Stress, anxiety disorders, depression, burnout
Medical conditions: Chronic pain, heart disease, respiratory disorders, thyroid conditions
Environmental factors: Noise, light exposure, an uncomfortable sleep environment
Lifestyle factors: Shift work, irregular sleep schedules, excessive caffeine or alcohol intake
Medications: Certain blood pressure medications, corticosteroids, or antidepressants can interfere with sleep
Other sleep disorders: Such as restless legs syndrome or sleep apnea

Symptoms

Common symptoms of insomnia include:

Difficulty falling asleep (taking longer than 30 minutes)
Frequent nighttime awakenings with trouble returning to sleep
Waking up too early in the morning
Non-restorative or unrefreshing sleep
Daytime sleepiness and fatigue
Problems with concentration and memory
Mood disturbances, irritability, or increased anxiety
Reduced performance at work or in everyday life

Diagnosis

Insomnia is primarily diagnosed through a thorough medical history and clinical interview. Additional diagnostic tools may include:

Sleep diary: Recording sleep and wake times over several weeks
Questionnaires: Standardized tools such as the Pittsburgh Sleep Quality Index (PSQI) or the Insomnia Severity Index (ISI)
Actigraphy: A wrist-worn device that monitors movement patterns over time to estimate sleep-wake cycles
Polysomnography: A comprehensive sleep study measuring brain activity, heart rate, breathing, and other parameters during sleep
Blood tests: To rule out underlying medical causes such as thyroid dysfunction

Treatment

Non-pharmacological Therapy

Cognitive Behavioral Therapy for Insomnia (CBT-I) is the recommended first-line treatment and has the strongest evidence base. It includes:

Sleep hygiene education (e.g., maintaining a consistent sleep schedule, avoiding screens before bedtime)
Stimulus control (reserving the bed only for sleep)
Sleep restriction therapy (temporarily limiting time in bed to consolidate sleep)
Relaxation techniques (progressive muscle relaxation, breathing exercises)
Cognitive restructuring (addressing negative beliefs and thoughts about sleep)

Pharmacological Therapy

Medications are generally used only short-term and as a supplement to behavioral approaches:

Benzodiazepines and Z-drugs (e.g., zolpidem, zopiclone): Short-term use only due to the risk of dependence
Low-dose antidepressants (e.g., doxepin, mirtazapine): Used when insomnia co-occurs with depression
Melatonin: Especially useful for delayed sleep phase disorders or in older adults
Orexin receptor antagonists (e.g., suvorexant): A newer drug class that promotes sleep by blocking wake-promoting signals

Complementary Measures

Regular physical activity, stress management, reducing caffeine and alcohol intake, and optimizing the sleep environment (temperature, darkness, quiet) can significantly improve sleep quality.

References

Riemann D. et al. - European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 2017; 26(6): 675-700.
Qaseem A. et al. - Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians. Annals of Internal Medicine, 2016; 165(2): 125-133.
World Health Organization (WHO) - Mental Health and Sleep. Available at: www.who.int

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