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Meniscus Transplantation – Procedure, Recovery & Risks

Meniscus transplantation is a surgical procedure in which a damaged or removed meniscus is replaced with donor tissue. It helps protect the knee joint from early arthritis.

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Things worth knowing about "Meniscus transplantation"

Meniscus transplantation is a surgical procedure in which a damaged or removed meniscus is replaced with donor tissue. It helps protect the knee joint from early arthritis.

What is Meniscus Transplantation?

Meniscus transplantation (also called meniscal allograft transplantation) is an orthopaedic surgical procedure in which a missing or severely damaged meniscus is replaced with donor meniscus tissue (an allograft). The meniscus is a crescent-shaped cartilage disc located in the knee joint. It acts as a shock absorber, stabilises the joint, and evenly distributes load across the cartilage. When the meniscus is absent or severely damaged, the risk of early-onset knee osteoarthritis increases significantly.

Indications

Meniscus transplantation is typically considered when:

  • a meniscus has been removed via a total meniscectomy (complete surgical removal),
  • the patient suffers from persistent knee pain and functional limitations,
  • the articular cartilage is still largely intact (no advanced osteoarthritis),
  • the patient is relatively young (typically under 50 years of age) and wishes to remain physically active.

The procedure is not suitable for patients with already advanced gonarthrosis (knee osteoarthritis), significant axial malalignment, or serious comorbidities.

Surgical Procedure

The surgery is typically performed arthroscopically (minimally invasive keyhole surgery) or as a combined arthroscopic-open procedure. Donor tissue – a fresh-frozen or cryopreserved meniscal allograft – is carefully sized to match the anatomy of the recipient and then fixed within the knee joint. Fixation is achieved using bony anchor points (bone plugs or tunnels) and special sutures that attach the graft to the joint capsule.

Postoperative Care and Rehabilitation

Recovery after meniscus transplantation requires a structured and progressive rehabilitation programme:

  • In the first weeks, the knee is partially immobilised and weight-bearing is restricted.
  • Physiotherapy exercises to restore range of motion and muscle strength begin early.
  • Return to sporting activities is generally possible after 6 to 12 months.
  • Regular follow-up examinations (clinical and imaging) are necessary to monitor the healing process.

Benefits and Risks

In suitable patients, meniscus transplantation can lead to significant pain reduction and improved knee function, and may delay the progression of knee osteoarthritis. Success rates are good with careful patient selection, with studies reporting satisfaction rates of up to 80–90%.

Possible risks and complications include:

  • Graft failure or loosening
  • Infection at the surgical site
  • Thrombosis (blood clots)
  • Re-injury of the transplanted meniscus
  • General surgical and anaesthetic risks

Alternatives

Depending on the clinical findings, the following alternatives to meniscus transplantation may be considered:

  • Meniscal repair (if viable meniscal tissue remains)
  • Partial meniscectomy (removal of the damaged portion only)
  • Conservative treatment with physiotherapy and pain management
  • Total knee replacement in cases of advanced arthritis

References

  1. Elattar O. et al. - Meniscal Allograft Transplantation. In: Journal of the American Academy of Orthopaedic Surgeons, 2017.
  2. Cole B.J. et al. - Outcomes After Meniscal Allograft Transplantation. In: The American Journal of Sports Medicine, 2011.
  3. Abram S.G.F. et al. - Meniscal transplantation: a systematic review and meta-analysis. In: Knee Surgery, Sports Traumatology, Arthroscopy, 2021.
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