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Nausea – Causes, Symptoms and Treatment

Nausea is an uncomfortable sensation in the stomach often accompanied by the urge to vomit. It is a common symptom with many possible causes.

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Things worth knowing about "Nausea"

Nausea is an uncomfortable sensation in the stomach often accompanied by the urge to vomit. It is a common symptom with many possible causes.

What is Nausea?

Nausea is an unpleasant, often wave-like sensation in the upper abdomen or throat that is frequently accompanied by the urge to vomit. It is not a disease in itself but rather a symptom that can point to a wide variety of underlying conditions. Nausea can be short-lived and harmless, but it can also indicate a serious medical condition that requires professional evaluation.

Causes

The causes of nausea are diverse and can be grouped into several categories:

Gastrointestinal Causes

  • Gastrointestinal infections (e.g., viral or bacterial gastroenteritis)
  • Food poisoning
  • Gastritis (inflammation of the stomach lining)
  • Peptic ulcers or gastroesophageal reflux disease (GERD)
  • Irritable bowel syndrome

Medications and Substances

  • Chemotherapy for cancer treatment
  • Antibiotics, pain relievers (e.g., ibuprofen, aspirin)
  • Alcohol or drug misuse

Pregnancy

Nausea is especially common during the first trimester of pregnancy, often referred to as morning sickness. It is triggered by hormonal changes, particularly a rise in the hormone hCG (human chorionic gonadotropin).

Neurological and Psychological Causes

  • Migraine headaches
  • Vertigo and balance disorders (e.g., Meniere's disease)
  • Motion sickness (kinetosis)
  • Anxiety disorders and severe stress

Other Causes

  • Cardiac conditions (e.g., a heart attack can present with nausea)
  • Kidney or liver disease
  • Thyroid disorders
  • Postoperative nausea and vomiting following anesthesia

Symptoms and Associated Signs

Nausea rarely occurs in isolation. Common accompanying symptoms include:

  • Vomiting
  • Dizziness or lightheadedness
  • Increased salivation
  • Pallor and sweating
  • Abdominal pain or stomach cramps
  • Loss of appetite
  • Rapid heartbeat (in some cases)

Diagnosis

Because nausea is a symptom rather than a standalone condition, the diagnostic process focuses on identifying the underlying cause. A healthcare provider will begin with a thorough medical history, asking questions such as:

  • When does the nausea occur – in the morning, after eating, or in specific situations?
  • Are there accompanying symptoms such as vomiting, pain, or fever?
  • What medications are currently being taken?
  • Is there a possibility of pregnancy?

Depending on the suspected cause, the following investigations may be conducted:

  • Blood and urine tests
  • Abdominal ultrasound
  • Upper endoscopy (gastroscopy)
  • Imaging studies such as CT or MRI for neurological concerns

Treatment

Treatment always depends on the underlying cause. The following measures may help:

General Measures

  • Rest and relaxation
  • Adequate fluid intake (water, herbal tea) to prevent dehydration
  • Light, easily digestible foods (e.g., crackers, rice, bananas)
  • Fresh air and an upright posture

Home Remedies

  • Ginger (as tea or capsules) has demonstrated antiemetic properties
  • Peppermint tea can have antispasmodic and soothing effects
  • Acupressure at the P6 point (inner wrist) may help with motion sickness

Medications

For more severe or persistent nausea, antiemetic medications are used, such as:

  • Dimenhydrinate (e.g., for motion sickness)
  • Metoclopramide (MCP) for gastrointestinal nausea
  • Ondansetron for chemotherapy-induced nausea and vomiting
  • Domperidone to promote gastric emptying

When to See a Doctor

In most cases, nausea is harmless and resolves on its own. However, medical attention is recommended if:

  • Nausea persists for more than 2–3 days
  • Projectile or bloody vomiting occurs
  • Severe abdominal pain or fever is present
  • Signs of dehydration appear, such as dry mouth, dizziness, or significantly reduced urination
  • Nausea occurs following a head injury
  • Nausea is severe during pregnancy (hyperemesis gravidarum)

References

  1. World Health Organization (WHO): Symptom Management Guidelines. Geneva: WHO Press, 2023.
  2. Hasler WL. - Nausea, Vomiting, and Indigestion. In: Harrison's Principles of Internal Medicine, 21st Edition. McGraw-Hill Education, 2022.
  3. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Nausea and Vomiting – Overview and Treatment Options. U.S. Department of Health and Human Services, 2023.

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