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Mannose - natural simple sugar to support bladder health

D-Mannose helps with recurring bladder infections by preventing bacteria from adhering to the bladder. Natural, well tolerated & has no effect on blood sugar.

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Things worth knowing about "Mannose"

D-mannose is a naturally occurring simple sugar (monosaccharide) that is closely related to glucose and is also found in small quantities in the human body and in fruits such as apples, cranberries, peaches and berries.

Unlike conventional sugar, D-mannose is hardly metabolised by the body, but is excreted almost unchanged in the urine via the kidneys - a property that makes it particularly valuable for bladder and urinary tract health. D-mannose is used in particular for recurring urinary tract infections (e.g. cystitis). 

Its effect is based on a mechanical principle: many disease-causing E. coli bacteria, which cause over 80% of all bladder infections, attach themselves to the bladder mucosa via special fimbriae (hair structures). D-mannose can bind to these fimbriae and thus prevent the bacteria from attaching to the mucous membrane - the pathogens are flushed out with the urine. As a result, D-mannose can reduce recurrent infections without disrupting the natural intestinal flora - an advantage over antibiotics.

Since D-mannose does not interfere with the sugar metabolism, it hardly increases the blood sugar level and is also suitable for diabetics. It is usually taken as a powder or capsule; the combination with cranberry extract, probiotics or bearberry leaves has proved particularly effective. Side effects are rare and are usually due to very high dosages or individual intolerances. 

Important features of D-Mannose: 

  • Simple sugar that is excreted via the kidneys 
  • Prevents the adhesion of E. coli bacteria to the bladder wall 
  • Effective for recurrent urinary tract infections 
  • Well tolerated, also suitable for diabetics 
  • Application as powder or capsules, often combined with plant extracts 

Literature

  • Kranjčec, B. et al. (2014). "D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomised clinical trial." World Journal of Urology. 
  • Domenici, L. et al. (2016). "D-mannose: a promising support for acute urinary tract infections in women." European Review for Medical and Pharmacological Sciences. 
  • Charron, M. J. et al. (1989). "Mannose metabolism in humans." The American Journal of Clinical Nutrition.

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