Epigallocatechin gallate (EGCG) - benefits for metabolism, blood sugar & cell regeneration
Epigallocatechin gallate (EGCG) is a powerful antioxidant from the catechin group and one of the main active ingredients in green tea.
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Epigallocatechin gallate (EGCG) is a powerful antioxidant from the catechin group and one of the main active ingredients in green tea.
EGCG It is a phytochemical and is particularly valued for its health-promoting properties, which include supporting metabolism, regulating blood sugar levels, anti-inflammatory properties and protecting cells from oxidative stress. EGCG has been shown to have positive effects on blood sugar metabolism by improving insulin sensitivity and promoting the uptake of glucose into the cells. The antioxidant therefore helps to stabilise blood sugar levels, which is of particular interest to people with insulin resistance or prediabetes.
EGCG also has the ability to promote autophagy. This describes the natural cleansing and regeneration process of the cells, in which damaged cell components and unusable cell structures are broken down and recycled. EGCG stimulates the so-called AMPK signalling pathway (AMP-activated protein kinase), a central energy regulator in the cell. AMPK is known to promote autophagy, especially in cellular stress situations such as fasting or nutrient deficiency. By activating AMPK, EGCG can improve the energy efficiency of the cell and trigger autophagy in a targeted manner. In addition, the mTOR signalling pathway is a known inhibitor of autophagy. EGCG can suppress mTOR, a regulator of various cells, and thus enhance autophagy. This mechanism is particularly important for cancer research, as increased autophagy promotes the disposal of damaged cell components and breaks down potentially cancer-promoting cell structures.
A similar approach to promoting autophagy is also attributed to spermidine, a natural compound found in foods such as wheat germ. Spermidine and EGCG act synergistically at the cellular level by promoting the cellular cleansing and regeneration process. This combination could be particularly helpful in minimising cell damage and preventing age-related diseases.
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