Angiogenesis - formation of new blood vessels: importance for healing, tumour growth and therapy
Angiogenesis is the formation of new blood vessels - central to healing, but also to tumour growth. Find out more about physiological functions, pathological processes and therapeutic approaches.
Wissenswertes über "Angiogenesis"
Angiogenesis is the formation of new blood vessels - central to healing, but also to tumour growth. Find out more about physiological functions, pathological processes and therapeutic approaches.
Angiogenesis refers to the new formation of blood vessels from existing vessels. This physiological process is essential for wound healing, tissue supply, organ development and reproduction. At the same time, angiogenesis also plays a central role in pathological processes, in particular in tumour growth, chronic inflammation and eye diseases.
pro- and anti-angiogenic factors. It is activated by:
- Wound healing
- Menstrual cycle
- Embryonic development
- Adaptation to oxygen deficiency (hypoxia)
endothelial cells to proliferate, migrate and sprout vessels.
dysregulated or excessive angiogenesis is associated with numerous diseases:
- Cancer: Tumours stimulate angiogenesis to supply themselves with nutrients (tumour angiogenesis)
- Rheumatoid arthritis: Inflammatory changes in the joints form new blood vessels
- Diabetic retinopathy & macular degeneration: pathological vascularisation in the eye
- Psoriasis: vascular growth in inflamed skin tissue
goal and a tool of modern medicine:
1. angiogenesis inhibition (anti-angiogenesis):
- Stop tumour growth, e.g. with VEGF inhibitors
- 2. promotion of angiogenesis (pro-angiogenesis):
- Healing of circulatory disorders (e.g. chronic wounds or heart attacks)
- TRAPTRAP study is taking a different approach: The protein tTF-NGR is used to specifically interrupt the tumour supply by targeting the tTF-NGR.strong data-start=""2461"" data-end=""2529"">selectively blocking and occluding tumour-associated angiogenesis - a new therapeutic approach that exploits angiogenesis to specifically starve tumours.
Literature references:
- Nature Reviews Drug Discovery.
- Nature.
- Nature Reviews Cancer.
Meistgekaufte Produkte
For your iron balance
Specially formulated for your iron balance with plant-based curry leaf iron, Lactoferrin CLN®, and natural Vitamin C from rose hips.
For your universal protection
As one of the most valuable proteins in the body, lactoferrin is a natural component of the immune system.
For Healthy Oral Flora & Dental Care
Formulated lozenges with Dentalac®, probiotic lactic acid bacteria, and Lactoferrin CLN®The latest entries
3 Posts in this encyclopedia categoryDunphy Sign
Most read entries
3 Posts in this encyclopedia categoryMagnesiumcarbonat
Calorie content
Cologne list
Related search terms: Angiogenesis-en